KHẢO SÁT NỒNG ĐỘ PTH Ở BỆNH NHÂN BỆNH THẬN MẠN GIAI ĐOẠN CUỐI THẬN NHÂN TẠO CHU KỲ TẠI BỆNH VIỆN THẬN HÀ NỘI NĂM 2022

Abstract

End-stage renal disease is one of the major global health burdens with many complications affecting the patient's quality of life, specifically secondary hyperparathyroidism. Objectives: Describe PTH levels and investigate the association between PTH levels and a number of clinical and subclinical factors in the end-stage renal disease patients on dialysis. Methods: Cross-sectional study on 327 end-stage renal disease patients on maintenance hemodialysis at Hanoi Kidney Hospital in 2022. Results: The average age of patients was 54.48 ± 14.49 years with 47.7% male and 52.3% female. The average PTH concentration was 731.3 ± 600.81 pg/ml, only 15.0% of patients had PTH reaching the recommended threshold of K/DOQI 2003 (150-300 pg/ml) and up to 71.3% Patients whose PTH exceeds this threshold. Patients with PTH exceeding the recommended threshold are positively associated to the duration of hemodialysis, blood phosphorus concentration and blood Ca × P product. Conclusion: The majority of hemodialysis patients have PTH concentrations exceeding the recommended threshold of K/DOQI 2003. This rate is positively associated to the duration of hemodialysis, blood phosphorus concentration and blood Ca × P product.