HIỆU QUẢ CỦA BIỆN PHÁP TRUYỀN INSULIN TRONG ĐIỀU TRỊ VIÊM TỤY CẤP CÓ TĂNG TRIGLYCERIDE

Abstract

Objectives: Evaluate the effectiveness of insulin infusion in the treatment of acute pancreatitis with increased triglyceride. Subjects and Methods: The study used a cross-sectional design, uncontrolled intervention with follow-up and before-after comparison on 32 patients with acute pancreatitis with increased triglycerides at Vinh City General Hospital, using the method Prospective data collection method from February 2023 to March 2024. Results: Blood triglyceride levels decreased over time of treatment, after 3 days, 24/32 patients had TG < 5.6 mmol/L. Clinical symptoms of acute pancreatitis improve significantly after an average of 2-4 days. Severity assessment scores (SOFA, abdominal pressure) decreased significantly after 1 day of treatment (p<0.05). As a result, 30/32 patients were discharged from the hospital (93.8%), and 2/32 patients referred to higher level hospitals (6.2%) had multiple organ failure. 10/32 patients (31.2%) experienced moderate and mild complications of hypokalemia. There were 5/32 patients (15.6%) with grade 1 hypoglycemia. Conclusions: Insulin infusion therapy for patients with acute pancreatitis with mild and moderate triglyceride elevation gives good results, helping to quickly improve TG elevation. The therapy is relatively safe, with few mild or moderate complications