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Date Published: 19/08/2024
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DOI: https://doi.org/10.51298/vmj.v541i2.10761
Issue
Vol. 541 No. 2 (2024)
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Các bài báo
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Nguyễn , V. P., Lê , V. H., & Trương , V. L. (2024). IDENTIFY GENOTYPES AND THE RELATIONSHIP BETWEEN GENE TYPE DISTRIBUTION WITH SOME EPIDEMIOLOGICAL CHARACTERISTICS IN CHRONIC HEPATITIS C PATIENTS TREATED IN NGHE AN. Vietnam Medical Journal, 541(2). https://doi.org/10.51298/vmj.v541i2.10761

IDENTIFY GENOTYPES AND THE RELATIONSHIP BETWEEN GENE TYPE DISTRIBUTION WITH SOME EPIDEMIOLOGICAL CHARACTERISTICS IN CHRONIC HEPATITIS C PATIENTS TREATED IN NGHE AN

Văn Phúc Nguyễn , Văn Hưng Lê , Văn Lợi Trương

Main Article Content

Abstract

Objective: Identify genotypes and the relationship between genotype distribution and epidemiological characteristics in patients with chronic hepatitis C. Research subjects and methods: patients diagnosed with chronic hepatitis C virus at Nghe An General Hospital in the period from August 1, 2022 to July 31, 2023 were tested for genotype. using gene sequencing technology. Results: Among a total of 98 patients with hep C who were tested to determine their genotypes using gene sequencing technology, genotype 1 had 47 patients (47.9%), genotype 6 had 43 patients (43.8). %), genotype 2 had 01 patient (0.01%) and 07 patients (0.07%) whose genotype could not be determined. In the group of patients whose genotype was determined, subtype 1b accounted for the largest proportion with 36 cases (37%), followed by subtype 6a with 30 cases (31%), subtype 1a with 11 cases (11%). There is no association between HCV genotype and subtype with age, gender and geographical area. Conclusion: Genotype 1 accounts for the highest proportion, in which subtype 1b predominates. There is no relationship between genotype, subtype and gender, age and geographical area

Article Details

Keywords

HCV genotype gene sequencing, Hepatitis C, HCV subtypee

References

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