ĐÁNH GIÁ TÁC DỤNG CẢI THIỆN CHỈ SỐ LIPID MÁU CỦA BÀI THUỐC BÁN HẠ BẠCH TRUẬT THIÊN MA GIA GIẢM TRÊN BỆNH NHÂN CÓ RỐI LOẠN LIPID MÁU

Abstract

Background: Dyslipidemia are a risk factor for many serious cardiovascular and metabolic diseases. The combination of modern medicine and traditional medicine in managing lipid disorders is a trend that many clinicians are interested in because it enhances therapeutic effects and reduces unwanted side effects. Objectives: To assess the clinical characteristics and comparing the lipid-improving effects of the modified Banxia Baizhu Tianma Tang combined with 20mg Atorvastatin with the standard regimen of  Atorvastatin 20mg alone. Materials and methods: This study is a randomized controlled clinical trial involving 74 patients diagnosed and indicated for treatment of dyslipidemia. The patients are divided into two groups: Group 1 uses Banxia Baizhu Tianma Tang combined with Atorvastatin 20mg, and Group 2 uses Atorvastatin 20mg alone. The treatment is administered continuously for 30 days at Can Tho Hospital of Traditional Medicine from February 2023 to May 2024. Results: The average age of the patients is 57.99 ± 11.59 years, with the ratio of females to males being 1.96:1. The proportion of elderly patients is 48.65%, and 40.5% have grade I obesity. The combination therapy of the modified traditional medicine formula Banxia Baizhu Tianma Tang and Atorvastatin 20mg significantly improved lipid levels (p<0.01) after 30 days of treatment. However, the difference was not statistically significant compared to the control group, which used only Atorvastatin 20mg. Conclusion: Banxia Baizhu Tianma Tang significantly improved blood lipid levels and markedly improved symptoms of píxū Tánshī according to traditional medicine.