CĂN NGUYÊN VI KHUẨN GÂY VIÊM PHỔI LIÊN QUAN THỞ MÁY TẠI KHOA HỒI SỨC TÍCH CỰC NGOẠI KHOA BỆNH VIỆN HỮU NGHỊ ĐA KHOA NGHỆ AN

Abstract

Objective: Identify the bacterial causes of ventilator-associated pneumonia at the Department of Surgical Intensive Care of Nghe An General Friendship Hospital from 2022 to 2023. Subjects and methods: a cross-sectional descriptive study on 110 patients diagnosed with ventilator-associated pneumonia from October 2022 to October 2023 at the Department of Surgical Intensive Care, Nghe An General Friendship Hospital. Results: The positive sputum culture rate was 82.7%. Acinetobacter baumannii accounts for the highest proportion at 43.1%, followed by Klebsiella pneumoniae accounts for 25.5%, Pseudomonas aeruginosa accounts for 13.7%, and Escherichia coli accounts for 3.9%. Gram-positive bacteria are Staphylococcus aureus, accounting for 7.8%. A. baumannii is resistant to many commonly used antibiotics today at a very high rate, > 80% resistant to piperacillin/tazobactam antibiotics, 3rd - 4th generation cephalosporins, and carbapenems. K.pneumoniae strains are resistant to β-lactam antibiotics at a rate of more than 75%, and> 90% are resistant to 3-4 generation cephalosporins. P. aeruginosa is > 75% resistant to most antibiotics. All Staphylococcus aureus strains were resistant to methicillin, 100% sensitive to vancomycin and linezolid, utterly resistant to Penicillin G. Escherichia coli was resistant to quinolone at a rate of > 90%, 62.5% resistant to Ceftazidime, 100% resistant to cefoperazone, cefuroxime, piperacillin/tazobactam, amoxicillin/clavulanic acid. Escherichia coli is also sensitive to Amikacin at a rate of 62.5%. Conclusion: The leading causes of ventilator-associated pneumonia are A.baumannii and K. pneumoniae. Pathogenic bacterial strains are resistant to many antibiotics at high rates.