ĐÁNH GIÁ ĐẶC ĐIỂM CHẤT LƯỢNG MÔ DÂY RỐN THU THẬP TẠI BỆNH VIỆN BƯU ĐIỆN

Abstract

Umbilical cord tissue has been a potential source of mesenchymal stem cells for regenerative medicine and therapy for decades. However, the process of collecting umbilical cord tissue always has the risk of poor sample quality and the incidence of fungal and bacterial infections that can affect the preservation and future treatment process. This study was conducted to evaluate the initial quality of umbilical cord tissue collected and finding the role of the factors and the results in collected umbilical cord tissue. A cross-sectional descriptive study on 126 umbilical cord tissue samples collected for autologous purposes at Stem cell and Genetic Center, Buu Dien Hospital from April 2023 to April 2024. Results showed that the proportion of boys is higher than girls (65.1% and 34.9%). The majority of second-born babies had umbilical cord tissue saved (71.6%). The average age of pregnant women with umbilical cord tissue saved was 32.9 ± 5.8 years old. The average age of the fetus at birth is 38.2 ± 1.2 weeks, highest in the 37 - 38 weeks group, is about 51.3%. Microbiological testing showed 1 sample positive with bacteria and fungi with the proportion is 0.8%. All samples have standard color, freshness, size and shape.