THE CLINICAL FEATURE AND SURGICAL RESULTS OF GASTRIC CANCER PERFORATION AND GASTRODUODENAL ULCER PERFORATION IN PATIENT HAVING CANCER DISEASES

Nguyên Hưng Thái, Văn Hạnh Mai

Main Article Content

Abstract

Study aim: 1. Evaluate the clinical and paraclinical feature of gastric cancer perforation and gastroduodenal ulcer perforation in patient having cancer diseases. 2. The surgical results of gastric cancer perforation and gastroduodenal perforation. The results: There were 46 patients, male 91,3%, female 8,7%, mean age 59,71 years, Subgroup of gastric cancer perforation was 26 patients, subgroup gastroduodenal ulcer perforation was 20 patients; Of them, 76% had strong abdominal pain, rebound tenderness. Abdominal X ray showed subphrenic air in 35 patients. CT scan revealed intra abdominal air and liquid in 76% and thickened wall of stomach with intraabdominal lymph nodes in 22 patients. Operation performed: subtotal gastrectomy with D2 lymphadenectomy in 23 patients; Simple suture in one patients; Suture with drainage tube (procedure of Newmann) in one patient, total gastrectomy with  left pancreatic and splenectomy in 1 patient. Death and complication: - One died due to disseminated intravascular Coagulation on  8 nd day post gastrectomy, - One patient had intra-abdominal bleeding < 24h post operation (reoperation for hemostasis) - One had adhesive small bowel  obstruction < 1 month (reoperation) - One had  intra abdominal abscess that healing by ultrasound guide drainage. Histopathology: 65,4% had Stage III-IV of gastric cancer. Conclusion: The surgical procedure for gastric cancer perforation should be divided into 2 procedures: The first: simple suture of perforation and abdominal lavage for peritonitis. The second: radical gastrectomy and D2 lymphadenectomy in order to have the elevated R0 resection and low mortality and also elevated 5 year survival rate more than 50%. It is advisable not to do palliative gastrctomy or non-radical resection  due to peritonitis that could have high mortality and low rate  of 5 years survival. - For gastroduodenal perforation: Laparoscopic suture with lavage is operation of choice. 2/3 gastrectomy and ulcer excluded or excised  and duodenostomy  should be performed in bleeding and posterior duodenal ulcer perforation that eroded to gastroduodenal artery and head of pancreas.

Article Details

References

Sara Di Carlo et al. Perforated gastric cancer: acritical appraisal. Discov Oncol 2021: 12:15 :1-10.
2. Hata T, Sakata N, Kudoh K, Shibata C, Unno M. The best surgical approach for perforated gastric cancer one stage vs two stage gastrectomy. Gastric cancer. 2014:17: 578-587.
3. Fisher BW. Urgent Surgery for gastric carcinoma: a study of national cancer database. J Surg Res.2020; 245: 619-628.
4. Kim HS, Lee JH, Kim MG. Outcome of laparoscopic primary gastrectomy with curative intent for gastric perforgation: Experience from single surgeon. Surg Endosc. 2020 .
5. Chung KT, Shelat VG. Perfogated peptic ulcer-an update. Word J Gastrointestinal Surg. (2017) 8:1-127.
6. Lehnert et al. Two-stage radical gastrectomy for perforated gastric cancer. Eur J Surg Oncol. 2000; 26: 780-4.
7. Fukuda N et al. Perforated gastric carcinoma treated with laparoscopic omental patch repaire followed by open radical surgery- Report a case. J Jpn Surg Assoc. 2005; 66: 243-5:
8. Tan KK, Quek TJL, Wong N, Li KK. Emergency surgery for perforated gastric malignancy: an institutor's experience and rewiew of literature. J Gastrointest Onco. 2011: 2(1):13-18