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EVALUATION OF THE EFFICACY OF ONDASETRON COMBINATION WITH DEXAMETHASONE IN PREVENTING NAUSEA AND VOMITING AFTER LAPAROSCOPIC APPENDECTOMY
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Abstract
Objective: To compare the efficacy of ondansetron alone versus the combination of ondansetron and dexamethasone in preventing postoperative nausea and vomiting (PONV) after laparoscopic appendectomy at 175 Military Hospital from January 2021 to May 2022. Subjects and Methods: This was a prospective, descriptive study comparing two groups. Group O received 4 mg of ondansetron, and Group OD received 4 mg of ondansetron combined with 4 mg of dexamethasone. Results: The incidence of postoperative nausea in Group O was 6.1%, while in Group OD it was 6.1%. The incidence of postoperative vomiting in Group O was 6.1%, compared to 4.1% in Group OD, with no statistically significant difference. Additionally, 2.1% of patients in Group OD required "rescue" treatment for vomiting, whereas no patients in Group O needed "rescue" treatment, a difference that was not statistically significant. Conclusion: There was no significant difference in the efficacy of ondansetron combined with dexamethasone compared to ondansetron alone in preventing postoperative nausea and vomiting.
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Keywords
nausea, vomiting, ondasetron, dexamethasone.
References
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