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CLINICAL AND PARACLINICAL CHARACTERISTICS AND TREATMENT RESULTS OF PNEUMONIA WITH PCR ADENOVIRUS POSITIVE IN CHILDREN AT PEDIATRIC CENTER OF BACH MAI HOSPITAL
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Abstract
Objective: To describe the clinical and paraclinical characteristics and treatment results of pneumonia with PCR adenovirus positive at the Pediatric Center – Bach Mai Hospital. Subject and Method: This descriptive study on 50 patients were diagnosed pneumonia with PCR Adenovirus positive from September 2022 to November 2022 treated at the Pediatric Center be long to Bach Mai Hospital. Result: The male and female ratio is 31/19, upper 12 months of age patients accounted for 82%. The most common symptoms are cough (94%), fever (92%), vomiting (60%), conjunctivitis (40%), and difficulty breathing (24%). Tachypnea is the most common physical symptom (38%), other less common physical symptoms are tachycardia (32%), dyspnea (24%). Lungs sounds showed symptoms of rales was 86%, of which wet rales in the lungs accounted for the highest rate at 54%, rales with wheezing, and rales with snoring (32.2%). All pediatric patients had leukocytosis (>10G/l), including 3 patients with white blood cell count >30G/L (6%). While the rate of normal platelet index is quite high (72%). Most patients showed increased CRP, accounting for 56%. Culture of nasopharyngeal fluid shows a negative rate of up to 80%. The most common bacteria is Haemophilus influenzae, followed by Moraxella catarhallis and Streptococcus pneumoniae. X-ray of the chest with images of damage mainly focused on clusters and diffuse opacities in both lungs accounting for 32.2% and 36.5% respectively. Lesions on Computed Tomography are seen in over 12.5% of pediatric patients. The main thing is the condition of consolidation in both lungs, accounting for a high rate (83.3%). Conclusion: Pneumonia caused by adenovirus is common in pediatric patients < 12 months old, mainly male children. The prominent symptoms are persistent cough, fever, and moist rales in both lungs. Most pediatric patients have leukocytosis and CRP, microbial co-infection, and severe pneumonia. The images on X-ray and CT are mainly lung consolidation.
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Keywords
Adenovirus, children, pneumonia.
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