SO SÁNH HIỆU QUẢ GIẢM TRIGLYCERIDE BẰNG LIỆU PHÁP TRAO ĐỔI HUYẾT TƯƠNG VÀ LIỆU PHÁP INSULIN TRONG ĐIỀU TRỊ BỆNH NHÂN VIÊM TỤY CẤP

Abstract

Objective: "Compare the effectiveness of triglyceride reduction by plasma exchange therapy and insulin therapy in the treatment of patients with acute pancreatitis". Subjects and Methods: Includes 30 AP patients with hyperglycemia treated with Insulin and TPE therapy at Thai Nguyen Nation Hospital from June 2022 to March 2024. Results: Both 2 groups have 3 patients developed severe AP. TG decreased <10 mmol/L after 24 hours of admission. TG decreased more within 24 hours after admission in the TPE group (66 ± 15%) compared to the Insulin group (55 ± 18%), p > 0.05. Cholesterol levels were also lower after 24 hours of hospitalization in the TPE group. TG decreased < 10 mmol/L on average after 1 day in the TPE group and after 2 days in the Insulin group. Both 2 groups had 3 cases of severe AP. Hospital stay was similar in both 2 groups, and survival rates were both 100%. There was one case of mild hypoglycemia in the Insulin group and some urticaria and hypotension in the TPE group. Conclusion: There is no difference in the effectiveness of TG reduction with TPE therapy and Insulin therapy in the treatment of patients with acute pancreatitis