ĐÁNH GIÁ CHỈ SỐ VIÊM MIỄN DỊCH HỆ THỐNG TRÊN BỆNH NHÂN VẢY NẾN

Abstract

Background: Evaluation of systemic immune inflammation index in patients with psoriasis. Methods: Cross-sectional descriptive study, including 80 patients diagnosed with psoriasis aged 18 years or older treated at Ho Chi Minh City Dermatology Hospital from December 2022 to October 2023 and 40 healthy people control. Results: The SII index value did not have a statistically significant difference between the group of patients with a family history and the group of patients without a family history (p = 0,9), between the group of patients with nail damage and the group of patients without nail damage (p = 0,2). No correlation was found between SII index value and patient age (r = 0,008, p = 0,94), age of onset (r = 0,006, p = 0,94), duration of disease (r = 0,01, p = 0,94). SII index values in psoriasis patients and PASI index have a moderate positive correlation (r = 0.4834, p < 0.001). The SII index value correlated weakly with hs-CRP concentration (r = 0,2507, p < 0,05) and erythrocyte sedimentation rate (r = 0,2411, p = 0,03). The SII index value has a strong positive correlation with both NLR (r = 0,908) and PLR (r = 0,7691) indexes. Conclusion: The systemic immunoinflammatory index was found to be significantly higher in patients with psoriasis than in healthy subjects. Systemic immune inflammation index can serve as an supporting method in the clinical diagnosis of psoriasis.