ACUTE RECURRENT PANCREATITIS: ETIOLOGY, CLINICAL AND PARACLINICAL CHARACTERISTICS AS WELL AS DISEASE SEVERITY

Đỗ Thục Anh Pham, Trường Sơn Nguyễn , Việt Hằng Đào

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Abstract

Objectives: (1) Investigate the causes of Acute recurrent pancreatitis (2) Study the relationship between the causes of acute recurrent pancreatitis and clinical and paraclinical characteristics as well as the severity of the disease. Materials and methods: Cross-sectional, prospective study on 106 patients with Acute recurrent pancreatitis treated from August 2023 to April 2024. Results: The proportion of causes of Acute recurrent pancreatitis by group: increased Triglyceride (50%); alcohol (27,4%); gallstones (8,5%); other ones (14,1%). The number of men is predominant in the group of due to alcohol, increased trigyceride and other ones. Patients with Acute recurrent pancreatitis due to increased triglyceride have lower total blood calcium levels than the remaining groups (P = 0.011). Recurrent pancreatitis due to alcohol had the lowest PH level and the highest CRP level among the four cause groups (P=0,023; P=0,004). The group with Acute recurrent pancreatitis due to gallstones had higher AST levels than the other groups (P=0,036). Patients with more than two episodes of pancreatitis had lower calcium levels than those with only one episode of pancreatitis (P=0,025). The severity of Acute recurrent pancreatitis was assessed by the 2012 revised Atlanta classification, the CTSI score, and the IMRIE score, with no significant differences among the causes. Conclusion: Pancreatitis due to hypertriglyceride was the common cause of Acute recurrent pancreatitis. Patients with two or more Acute recurrent pancreatitis had lower serum calcium levels than those with only one Acute recurrent pancreatitis.

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References

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