THE VALUE OF ULTRASOUND ELASTOGRAPHY IN DIAGNOSING THYROID NODULES AT CAN THO UNIVESITY OF MEDICINE AND PHARMACY HOSPITAL AND CAN THO CENTRAL GENERAL HOSPITAL IN 2022-2023

Thị Thúy Võ, Vũ Đằng Nguyễn , Hoàng Anh Nguyễn , Minh Phú Huỳnh, Ngọc Thuấn Bùi, Thanh Vy Đỗ

Main Article Content

Abstract

Objective: To describe some imaging characteristics of ultrasound elastography (UE) and determine the value of tissue UE in diagnosing thyroid nodules. Subjects and Methods: This cross-sectional descriptive study was conducted on 46 patients at Can Tho University of Medicine and Pharmacy Hospital and Can Tho Central General Hospital. Patients underwent 2D ultrasound to detect thyroid nodules and then had tissue elastography ultrasound (UE) performed, with pathological or cytological results of thyroid nodules available. Results: The average age of the patients was 49.65 ± 12.97 years, with the disease being more common in females than males at a ratio of 93.3%. The Tsukuba scoring system for UE images showed a majority at score 3 with a rate of 39.1% (18/46). Malignant thyroid nodules according to the Tsukuba score of 4 and 5 accounted for 55%, while scores of 1, 2, and 3 accounted for 3.8% (p < 0.01), with a sensitivity of 91.66%, specificity of 73.52%, positive predictive value of 55%, negative predictive value of 96.15%, and accuracy of 78.26%. For malignant thyroid nodules as determined by fine-needle aspiration (FNA), malignant UE results were 75%, higher than benign at 8.8% (p < 0.01), with a sensitivity of 75%, specificity of 91.17%, positive predictive value of 75%, negative predictive value of 91.17%, and accuracy of 86.95%. Conclusion: Cryotherapy is a simple, effective treatment method for cervical lesions, with few complications and a high satisfaction rate.

Article Details

References

1. Asteria C, Giovanardi A, Pizzocaro A, et al. US-Elastography in the Differential Diagnosis of Benign and Malignant Thyroid Nodules. Thyroid®. 2008/05/01 2008;18(5): 523-531. doi:10.1089/ thy.2007.0323
2. Rago T, Santini F, Scutari M, Pinchera A, Vitti P. Elastography: New Developments in Ultrasound for Predicting Malignancy in Thyroid Nodules. The Journal of Clinical Endocrinology & Metabolism. 2007;92(8):2917-2922. doi:10.1210/ jc.2007-0641
3. Rago T, Scutari M, Loiacono V, et al. Low Elasticity of Thyroid Nodules on Ultrasound Elastography Is Correlated with Malignancy, Degree of Fibrosis, and High Expression of Galectin-3 and Fibronectin-1. Thyroid®. 2017/01/01 2016;27(1): 103-110. doi:10.1089/ thy.2016.0341
4. Batur A, Atmaca M, Yavuz A, et al. Ultrasound Elastography for Distinction Between Parathyroid Adenomas and Thyroid Nodules. Journal of Ultrasound in Medicine. 2016/06/01 2016;35(6): 1277-1282. doi: https://doi.org/10.7863/ultra. 15.07043
5. Trần Thúy Hồng. Đặc điểm hình ảnh và giá trị của siêu âm trong chẩn đoán các tổn thương khu trú tuyến giáp. Luận văn Thạc sĩ Y học. Đại học Hà Nội; 2013.
6. Trịnh Thị Thu Hồng, Vương Thừa Đức. Hình ảnh siêu âm trong dự đoán ung thư bướu đa nhân. Tạp chí Y Dược học Thành phố Hồ Chí Minh. 2009;14(1):55-59.
7. Russ G. Risk stratification of thyroid nodules on ultrasonography with the French TI-RADS: description and reflections. Ultrasonography. 1 2016;35(1):25-38. doi:10.14366/usg.15027
8. Kim SJ, Kim EK, Park CS, Chung WY, Oh KK, Yoo HS. Ultrasound-Guided Fine-Needle Aspiration Biopsy in Nonpalpable Thyroid Nodules: Is It Useful in Infracentimetric Nodules? Yonsei Med J. 8/ 2003;44(4):635-640.
9. Afifi AH, Alwafa WAHA, Aly WM, Alhammadi HAB. Diagnostic accuracy of the combined use of conventional sonography and sonoelastography in differentiating benign and malignant solitary thyroid nodules. Alexandria Journal of Medicine. 2017/03/01/ 2017;53(1):21-30. doi: https://doi. org/10.1016/j.ajme.2016.02.007
10. Habib LAM, Abdrabou AM, Geneidi EAS, Sultan YM. Role of ultrasound elastography in assessment of indeterminate thyroid nodules. The Egyptian Journal of Radiology and Nuclear Medicine. 2016/03/01/ 2016;47(1):141-147. doi: https://doi.org/10.1016/j.ejrnm.2015.11.002