ĐÁP ỨNG ĐIỀU TRỊ Ở NGƯỜI BỆNH HIV/AIDS TẠI BỆNH VIỆN ĐA KHOA KHU VỰC GÒ CÔNG, TIỀN GIANG NĂM 2023

Abstract

Objective: Describe the current status of ARV treatment response in HIV/AIDS patients at Go Cong Regional General Hospital and identify some related factors. Research method: Cross-sectional descriptive design, conducted on 162 people with HIV/AIDS at Go Cong Regional General Hospital. Clinical information, CD4 testing, and viral load were collected through medical records. Logistic regression model was applied to identify associated factors. Results: The average CD4 count in the study was 547.1 ± 297.8 (cells/mm3) and the average viral load was 4.5 ± 9.7 (copies/mm3). 16.7% of patients had CD4 ≤ 250 cells/mm3, which is considered treatment failure according to the guidelines of the Ministry of Health. There were 19.1% of patients with viral load ≥ 20 copies/mm3. A longer the treatment duration (OR=1.24, 95%CI=1.06-1.45) was associated with a higher likelihood of experiencing treatment failure according to immune criteria. Patients treated with the second-line regimen (OR=0.07, 95%CI=0.01-0.95) were less likely to have the virus detected than patients treated with the first-line regimen. Patients taking more than 1 medication (OR=8.71, 95%CI=1.61-47.25) have a higher chance of detecting the virus than patients taking 1 medication. Conclusion: The response to immunological and virological treatment in HIV/AIDS patients at Go Cong area general hospital is good. Physicians need to pay attention to patients treated for long periods of time to control immunotherapy failure.