SURVEY OF BLOOD URIC ACID CONCENTRATION AT ADMISSION AND ITS RELATIONSHIP WITH SOME CLINICAL AND PARA-CLINICAL FEATURES IN PATIENTS WITH SEPTIC SHOCK
Main Article Content
Abstract
Objective: To investigate the rate of hyperuricemia and the relationship between blood uric acid levels and some clinical and paraclinical characteristics in patients with septic shock. Subjects and methods: 44 patients were diagnosed with septic shock according to Sepsis-3. Uric acid test performed at the time of admission, hyperuricemia is defined as blood uric acid concentration in men > 420 µmol/l and in women > 360 µmol/l. Results: 37/44 patients had hyperuricemia, accounting for 84.1%. SOFA score, blood urea concentration, blood creatinine concentration and blood lactate concentration in the group of patients with hyperuricemia were statistically significantly higher than the group of patients without hyperuricemia. There is a moderate positive correlation between blood uric acid levels and blood urea and creatinine levels, the correlation coefficients are 0.496 and 0.507, respectively, p<0.05. Conclusion: Hyperuricemia accounts for a fairly high rate, blood uric acid levels are positively correlated with blood urea and creatinine in patients with septic shock
Article Details
Keywords
hyperuricemia, sepsis, septic shock
References
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