ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG TIÊU CHẢY NHIỄM KHUẨN KÉO DÀI Ở TRẺ 6-24 THÁNG TẠI BỆNH VIỆN NHI TRUNG ƯƠNG

Abstract

Prolonged infectious diarrhea is commonly associated with pathogenic bacteria in pediatric patients, it causes electrolyte disorders, infection and malnutrition affecting the child’s development. Aim: To describe the clinical and laboratory characteristics of prolonged infectious diarrhea in children. Materials and methods: a prospective study was conducted on 67 children, aged 6-24 months, diagnosed with prolonged infectious diarrhea at the National Children’s Hospital from July 2023 to April 2024. Result: The mean age of children was 10.6 ± 4.3 months. The boy/girl ratio was 1.8/1. The most common clinical symptoms were anal redness (82.1%), anorexia (64.2%), fever (49.3%), vomiting (40.3%). The complete blood count showed an elevated white blood cells in 21.9%, the rates of children with low and high neutrophils was 45.% and 20.3%, respectively. The prevalence of low lymphocyte and eosinophilia was 23.4% and 29.7% respectively. 34.4% of children had anemia and 25.8% had an elevated CRP index. Stool examination analysis showed the rate of a positive with leukocytes was 68.7% and 31.3% positive with both red and white blood cells. Prevalence of fat malabsorption and lactose intolerance was 19.7% and 40.9%, respectively. The positive stool culture rate was low with E. coli. Conclusion: Prolonged infectious diarrhea occured in children 6-12 months old with common clinical symptoms of loose stools mixed with mucus or blood. The most common accompanying symptoms were anal redness, loss of appetite, fever and vomiting. Common blood tests were neutropenia and eosinophilia. The rate of children with the posositive stool culture was low and mainly with E. coli