THỰC TRẠNG KHÁNG KHÁNG SINH CỦA CÁC CHỦNG PSEUDOMONAS AERUGINOSA PHÂN LẬP TẠI BỆNH VIỆN ĐA KHOA TÂM ANH NĂM 2023

Abstract

Pseudomonas aeruginosa is a significant pathogenic bacterium, with increasing antibiotic resistance complicating treatment efforts. Methods: This cross-sectional study was conducted to examine the distribution characteristics and antibiotic resistance patterns of P. aeruginosa strains isolated at Tam Anh General Hospital in 2023. Results: The infection rate of P. aeruginosa was 0.5% (37 out of 7,196 samples), with the majority of strains isolated from respiratory specimens (62.2%). In positive cases, P. aeruginosa was predominantly found in internal medicine departments (78.4%), among patients aged 60 years and older (59.5%), and in male patients (62.2%). The strains exhibited the highest susceptibility to Piperacillin-Tazobactam (87.1%), followed by Ciprofloxacin (83.9%), Imipenem (83.1%), Meropenem (80.6%), Ceftazidime (78.6%), and Cefepime (75.0%). The lowest susceptibility was observed for Amikacin and Norfloxacin (60.0%) in strains isolated from urine. Conclusion: The prevalence of P. aeruginosa infection at Tam Anh General Hospital is low. Piperacillin-tazobactam is the most effective antibiotic for treating P. aeruginosa infections in this hospital setting.