CHARACTERISTICS OF MORBIDITY AND SOME RELATED FACTORS IN PRETERM NEONATES UNDER 34 WEEKS OF GESTATION
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Abstract
Background: preterm neonates have been proven to be at high risk for serious complications. The risk increases with greater prematurity and lower birth weight. Objectives: the study aims to describe the morbidity characteristics and analyze some related factors in preterm neonates under 34 weeks of gestation. Materials and methods: a case series included 39 preterm neonates under 34 weeks of gestation who were admitted for treatment at the Neonatal Intensive Care Unit, Dong Thap General Hospital from July 2023 to March 2024. Results: regarding general characteristics, the results showed that the majority were male (69.2%), most had a weight between 1500-2500g (84.6%), gestational age from 32 weeks to less than 34 weeks accounted for 84.6%, and the majority were spontaneous vaginal delivery (62.2%). The main morbidities indicated that pneumonia and newborn jaundice were very common (79.5% and 89.7%, respectively), meanwhile, the proportion of sepsis was 17.9%. The univariate analysis found no significant differences between maternal and neonatal characteristics including baby’s weight, gestational age, gender, mode of delivery, maternal age, and pregnancy abnormalities, and the incidence of pneumonia (p > 0.05). Similar results were found when analyzing the relationship with sepsis (p > 0.05). Regarding newborn jaundice, the results showed that the proportion of jaundice in male neonates was significantly higher than in female ones (p < 0.05). Conclusion: pneumonia and neonatal jaundice are the most common diseases in preterm neonates. There were no significant differences in the percentage of pneumonia and sepsis in preterm neonates based on variables such as baby’s weight, gestational age, and gender; however, male newborns have a significantly higher percentage of jaundice compared to female newborns.
Article Details
Keywords
premature neonates, 34 weeks of gestation, morbidity, related factors.
References
2. Bùi Thị Bích Hà, Nguyễn Minh Phương, Nguyễn Thị Thu Ba. Nghiên cứu đặc điểm lâm sàng, cận lâm sàng, đánh giá kết quả điều trị viêm phổi ở trẻ sơ sinh non tháng tại Bệnh viện Nhi Đồng Cần Thơ năm 2019-2020. Tạp chí Y dược học Cần Thơ. 2020; 30:15-22.
3. Nguyễn Thị Xuân Hương, Hoàng Thị Huế, Phạm Trung Kiên, Nguyễn Khang Sơn. Tình hình bệnh tật và tử vong sơ sinh tại khoa Nhi Bệnh viện Đa khoa Trung ương Thái Nguyên trong 3 năm (2008-2010). Tạp chí Y học Thực hành. 2012; 810(3):7-10.
4. Phạm Hồng Loan, Trần Quang Hiền, Võ Huỳnh Trang. Đánh giá kết quả và tìm hiểu một số yếu tố liên quan đến chăm sóc trẻ sơ sinh non tháng bằng phương pháp Kangaroo tại Bệnh viện Đa khoa khu vực Châu Đốc. Tạp chí Y Dược học Cần Thơ. 2023; 30:207-215.
5. Nguyễn Thị Mai, Nguyễn Văn Sơn, Nguyễn Việt Hùng. Đặc điểm lâm sàng, cận lâm sàng vàng da trẻ sơ sinh non tháng tại Bệnh viện Đa khoa Trung ương Thái Nguyên. Tạp chí Y học Thực hành. 2013; 879(9):58-62.
6. Howson C.P., Kinney M.V., McDougall L., Lawn J.E. Born too soon: preterm birth matters. Reprod Health. 2013; 10(Suppl 1):S1.
7. Mostafa S.A., Aljeesh Y., Hamad K.A., Alnahhal M. Risk factors of hyperbilirubinemia among admitted neonates in the Gaza strip: case control study. J Public Heatlth Res. 2017; 7(2):39-45.
8. Shuai X., Li X., Wu Y. Prediction for late-onset sepsis in preterm infants based on data from East China. Front Pediatr. 2022; 10:924014.
9. Tesfie T.K., Anlay D.Z., Abie B., et al. Nomogram to predict risk of neonatal mortality among preterm neonates admitted with sepsis at University of Gondar Comprehensive Specialized Hospital: risk prediction model development and validation. BMC Pregnancy Childbirth. 2024; 24(1):139.
10. Viorika E.M., Yantri E., Rusdi. The relationship between Bilirubin and Interleukin 4 levels in the jaundice preterm neonates. Int J Res Rev. 2023; 10(4):226-230.