ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG CỦA NHIỄM KHUẨN HUYẾT Ở TRẺ SƠ SINH TẠI KHOA SƠ SINH BỆNH VIỆN PHỤ SẢN HÀ NỘI

Abstract

Objective: This study aimed to describe some clinical and paraclinical characteristics of neonatal sepsis at the Neonatal Intensive Care Unit of Hanoi Obstetrics and Gynecology Hospital. Subject and method: A combined restrospective – prospective descriptive study of 118 neonates diagnosed with neonatal sepsis and had positive blood culture results at the Neonatal Intensive Care Unit of Hanoi Obstetrics and Gynecology Hospital from August 2022 to May 2024. Results: The average gestational age was 29.9 weeks, most of neonates weighed less than 1500g, there were 61% boys and 39% girls. The rates of infants with early onset sepsis and late onset sepsis were 27.1% and 72.9%. The common clinical signs were poor feeding (85.6%), tachypnea (56.8%), jaundice (55.1%), apnea ≥ 15 seconds (42.4%), lagathy (36.4%), tachycardia (35.6%), fever (28%). The common paraclinical features are increased CRP (51.7%), thrombocytopenia (45.8%), hyperglycemia (29.7%) and leukopenia (22%). The main cause of neonatal sepsis was Gram – negative bacteria accounting for 75.2%, in which E. coli and K. pneumonia are the most common. Gram – positive bacteria accounted for 19.8%, the most common were S. aureus and Group B Streptococcus. Conclusion: Neonatal sepsis was mainly a late onset, it was common in preterm infants having very low birthweight and extremely low birthweight. Clinical and paraclinical features were varied. Most of pathogens were Gram – negative bacteria