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Date Published: 24/09/2024
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DOI: https://doi.org/10.51298/vmj.v542i2.11112
Issue
Vol. 542 No. 2 (2024)
Section
Các bài báo
How to Cite
Nguyễn, T. D., Trần, N. D., & Nguyễn, T. T. L. (2024). EVALUATION OF CHANGES IN HYDROXYPROLINE CONCENTRATION IN PRESSURE ULCER TISSUE AFTER THE AUTOLOGOUS PLATELET RICH PLASMA. Vietnam Medical Journal, 542(2). https://doi.org/10.51298/vmj.v542i2.11112

EVALUATION OF CHANGES IN HYDROXYPROLINE CONCENTRATION IN PRESSURE ULCER TISSUE AFTER THE AUTOLOGOUS PLATELET RICH PLASMA

Tiến Dũng Nguyễn, Ngọc Diệp Trần, Thị Thái Linh Nguyễn

Main Article Content

Abstract

Objective: Aim of this study was to evaluate Hydroxyproline (Hyp) concentration in tissue at the site of pressure ulcers after Autologous Platelet Rich Plasma (PRP) therapy. Subjects and methods: A study was conducted on 20 patients with pressure ulcers, who were treated at the Wound Healing Center, National Burn Hospital, from September 2023 to March 2024. These patients were injected with autologous PRP at the pressure ulcer bed. Biopsy of tissure at the ulcer site to determine Hyp before and after 1 week, 2 weeks of the autologous PRP therapy. Results: The average Hyp concentration in tissue at the pressure ulcer bed after 1 week (1.93±0.48 pg/mg tissue) and 2 weeks (3.69±0.59 pg/mg tissue) of autologous PRP therapy, which increased statistically significantly compared to before the autologous PRP therapy (5.54±0.87 pg/mg tissue). Conclusion: The autologous PRP effectly promoted the healing of pressure ulcers through stimulating the Hyp concentration in ulcer tissue

Article Details

Keywords

Pressure ulcer, Hydroxyproline, Platelet Rich Plasma.

References

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