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MEAN PLATELET VOLUME (MPV) OF PATIENTS WITH PSORIASIS AND ITS RELATIONSHIP WITH THE SEVERITY OF THE DISEASE
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Abstract
Objective: To determine levels of mean platelet volume (MPV) of patients with psoriasis and its relationship to the severity of the disease. Methods: A case-control study was conducted on 90 patients with psoriasis at the Ho Chi Minh City Hospital of Dermato-Venereology in 2022 and 45 healthy people in the control group. Results: MPV in the psoriasis patient group was 9,4 ± 0,9 fL. MPV in the control group was 8,0 ± 0,9 fL. The MPV in the psoriasis patient group was significantly higher than the control group, with statistical significance at p < 0,001. Furthermore, the MPV in all four subgroups of psoriasis, including plaque psoriasis, pustular psoriasis, psoriatic arthritis, and erythrodermic psoriasis, was significantly higher compared to the control group (p < 0,001). Among them, the MPV was highest in the psoriatic arthritis group with a mean of 9,7 ± 0,9 fL, followed by the erythrodermic psoriasis group with a mean of 9,5 ± 1,1 fL, plaque psoriasis group with a mean of 9,5 ± 0,9 fL, and pustular psoriasis group with a mean of 9,0 ± 0,9 fL. The MPV showed a positive correlation with the PASI severity score (r = 0,334; p = 0,015). Conclusion: There was an increase in MPV in patients with psoriasis in general and in all four subgroups of psoriasis, including plaque psoriasis, pustular psoriasis, psoriatic arthritis, and erythrodermic psoriasis and the change is related to PASI.
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Keywords
mean platelet volume, MPV, plaque psoriasis, pustular psoriasis, psoriatic arthritis, erythrodermic psoriasis.
References
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