Article Sidebar
Views pdf: 0
EFFECTIVENESS OF ENDOSCOPIC SUBMUCOSAL DISSECTION IN THE TREATMENT OF PRE-CANCER AND EARLY-STAGE CANCER IN THE COLON AT THE GASTROENTEROLOGY AND HEPATOLOGY CENTER, BACH MAI HOSPITAL
Main Article Content
Abstract
Objective: To assess the efficacy of endoscopic submucosal dissection in the treatment of pre-cancer and early-stage cancer in the colon. Subjects and methods: A non-controlled clinical intervention was conducted on 30 patients with colorectal polyps treated by endoscopic submucosal dissection (ESD). All patients were followed up two months after treatment to assess for recurrence. Results: Before treatment, according to the JNET classification, the majority were type IIA (76.7%); according to the KUDO classification, type IIIL (63.3%), and 6 cases of early cancer. Results of ESD implementation: 100% of the technique was successful, mainly in over 30 minutes (76.7%), with no complications. The en-bloc resection rate was 100%, the R0 rate was 86.7%. After two months of follow-up, 100% of patients had healed scars and no recurrence. Conclusion: Submucosal dissection is an effective and safe technique in the treatment of pre-cancer and early-stage cancer in the colon
Article Details
Keywords
endoscopic submucosal dissection, colorectal cancer, polyp
References
2. Gao P, Zhou K, Su W, Yu J, Zhou P. Endoscopic management of colorectal polyps. Gastroenterol Rep (Oxf). 2023;11:goad027. doi:10.1093/gastro/goad027.
3. Okumura T, Hayashi T, Kudo SE, et al. Endoscopic submucosal dissection for colorectal neoplasms: Risk factors for local recurrence and long-term surveillance. DEN Open. 2024;4(1): e269. doi:10.1002/deo2.269.
4. Wang N, Shu L, Liu S, et al. Comparing endoscopic mucosal resection with endoscopic submucosal dissection in colorectal adenoma and tumors: Meta-analysis and system review. PLoS One. 2023;18(9): e0291916. doi:10.1371/ journal.pone.0291916.
5. Eun Na J, Kim B, Hoon Jung S, Choi A, Kim S, Kim TO. Usage trends of colorectal endoscopic submucosal dissection according to hospital types based on nationwide claims data. Medicine (Baltimore). 2023;102(43): e35514. doi:10.1097/ md.0000000000035514.
6. Niimi K, Fujishiro M, Kodashima S, et al. Long-term outcomes of endoscopic submucosal dissection for colorectal epithelial neoplasms. Endoscopy. 2010;42(09):723-729.
7. Saito T, Kobayashi K, Sada M, et al. Comparison of the histopathological characteristics of large colorectal laterally spreading tumors according to growth pattern. Journal of the anus, rectum and colon. 2019;3(4): 152-159.
8. Chow CWS, Fung TLD, Chan PT, Kwok KH. Endoscopic submucosal dissection for colorectal polyps: outcome determining factors. Surg Endosc. 2023;37(2): 1293-1302. doi:10.1007/ s00464-022-09672-2.
9. Singh RR, Nanavati J, Gopakumar H, Kumta NA. Colorectal endoscopic submucosal dissection in the West: A systematic review and meta-analysis. Endosc Int Open. 2023;11(11):E1082-e1091. doi:10.1055/a-2181-5929.
10. Kobayashi N, Takeuchi Y, Ohata K, et al. Outcomes of endoscopic submucosal dissection for colorectal neoplasms: Prospective, multicenter, cohort trial. Dig Endosc. 2022;34(5): 1042-1051. doi:10.1111/den.14223.