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Date Published: 17/10/2024
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DOI: https://doi.org/10.51298/vmj.v543i2.11384
Issue
Vol. 543 No. 2 (2024)
Section
Các bài báo
How to Cite
Phạm, V. D., Nguyễn, V. L., Trịnh , L. H., Nguyễn, T. P. T., Nguyễn, T. N., Trương, T. T. H., Hoàng, P. Q. T., Trần, H. P., Nguyễn, H. H., & Đặng, T. T. H. (2024). EVALUATION THE TREATMENT OUTCOME OF POTENTIALLY RESECTABLE COLORETAL CANCER LIVER METASTASES AT MILITARY CENTRAL HOSPITAL 108. Vietnam Medical Journal, 543(2). https://doi.org/10.51298/vmj.v543i2.11384

EVALUATION THE TREATMENT OUTCOME OF POTENTIALLY RESECTABLE COLORETAL CANCER LIVER METASTASES AT MILITARY CENTRAL HOSPITAL 108

Văn Dũng Phạm, Việt Long Nguyễn, Lê Huy Trịnh , Thị Phương Thảo Nguyễn, Thanh Ngọc Nguyễn, Thị Thảo Hiền Trương, Phan Quỳnh Trang Hoàng, Hoàng Phương Trần, Huy Hoàng Nguyễn, Thị Thu Hiền Đặng

Main Article Content

Abstract

Objectives: Evaluate treatment outcome in potentially resectable liver metastases coloretal cancer patients with combined chemotherapy and targeted drugs. Patients and methods: Combined retrospective and prospective study on 41 colorectal cancer with liver metastasis patients underwent combination chemotherapy with targeted drugs at Chemotherapy department, Military Central Hospital 108 between January 2020 and March 2024. Results: Mean age was 58,7 ± 12,8 (31-80). Male/Female ratio = 2,73/1. The overall response rate (ORR) was 80%, Successful conversion rate was 60.9%. The most common side effect was hepatic toxicity, neutropenia and neurotoxicity were mainly mild grade 1-2. Conclusions: Chemotherapy combined with targeted drugs of patients with colorectal cancer with liver metastases resulted in high response rate, feasible and tolerable toxicity.

Article Details

Keywords

Colorectal cancer.

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