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Date Published: 17/10/2024
Abstract Views: 141
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DOI: https://doi.org/10.51298/vmj.v543i2.11397
Issue
Vol. 543 No. 2 (2024)
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Các bài báo
How to Cite
Lê, H. L. H., & Nguyễn, V. A. (2024). STATUS OF ANTIMICROBIAL RESISTANCE OF STAPHYLOCOCCUS AUREUS STRAINS CAUSING WOUND INFECTIONS AT MILITARY HOSPITAL 103 IN 2022. Vietnam Medical Journal, 543(2). https://doi.org/10.51298/vmj.v543i2.11397

STATUS OF ANTIMICROBIAL RESISTANCE OF STAPHYLOCOCCUS AUREUS STRAINS CAUSING WOUND INFECTIONS AT MILITARY HOSPITAL 103 IN 2022

Hạ Long Hải Lê, Văn An Nguyễn

Main Article Content

Abstract

Objective: To investigate the antibiotic resistance status of Staphylococcus aureus strains causing wound infections at Military Hospital 103 in 2022. Subjects and methods: This is a cross-sectional study determining the antimicrobial resistance profile of Staphylococcus aureus strains isolated from wound exudates of patients at Military Hospital 103 in 2022. Results: A total of 195 pathogenic agents were isolated from wound exudates in 2022, of which 60 (30.8%) were Staphylococcus aureus. The study results showed that S. aureus was highly resistant to erythromycin and clindamycin (81.7%), followed by cefoxitin (80.0%) and tetracycline (71.7%). Conversely, some antibiotics showed lower resistance rates, such as trimethoprim/sulfamethoxazole (20.0%), gentamicin (16.7%), levofloxacin, ciprofloxacin, and moxifloxacin (15.0%), and rifampin (1.7%). Antibiotics such as tigecycline, vancomycin, teicoplanin, linezolid, quinupristin-dalfopristin, and nitrofurantoin were completely sensitive to S. aureus strains. Among the isolated Staphylococcus aureus strains, 80% were Methicillin-resistant S. aureus (MRSA), with the highest proportion found in surgical wards (60.4%) and patients from 41 to 65 years old (45.0%). Conclusion: The antibiotic resistance rate of S. aureus strains was alarmingly high, especially MRSA. S. aureus was the highest resistant to erythromycin, clindamycin, cefoxitin, and tetracycline. This research serves as a call to action for healthcare professionals, policymakers, and stakeholders to collaborate closely to protect antibiotic efficacy and ensure public health

Article Details

Keywords

Wound infection, Staphylococcus aureus, S. aureus, MRSA

References

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