TỶ LỆ VÀ ĐẶC ĐIỂM SUY GIÁP Ở BỆNH NHÂN ĐÁI THÁO ĐƯỜNG TÍP 2 CÓ BỆNH THẬN MẠN TẠI BỆNH VIỆN NỘI TIẾT TRUNG ƯƠNG

Abstract

Background: Hypothyroidism is a common disorder but it is usually misdiagnosed. Hypothyroidism has been associated with type 2 diabetes mellitus and chronic kidney disease. Objectives: Prevalence and features hypothyroidism in patients with type 2 diabetes mellitus and chronic kidney disease stage 3-5 at The National Hospital of Endocrinology. Method: A cross-sectional study was conducted on 190 diabetic patients with chronic kidney disease stage 3-5, The National Hospital of Endocrinology, Hanoi, Vietnam from October 2023 to May 2024. Result: Male account for 66,3%. The mean age was 69,92 ± 10,37 years, mean HbA1C was 9,03 ± 2,04%, mean eGFR was 38,65 ± 11,14 ml/m/1,73m², mean urine ACR was 89,75 ± 177,081mg/g. The prevalence of hypothyroidism was 22,1%, higher in female (37,5% vs 14,3%, p=0,01). The hypothyroidism group had a higher age (p=0,021), HbA1C (p=0,03), lower eGFR (p=0,006), Multivariate analysis identified significant associations between hypothyroidism and age (OR 1,077; p=0,033), HbA1C (OR 1,366; p=0,032), and Urine ACR (OR 4,731; p=0,024). Conclusion: Patients with type 2 diabetes mellitus and chronic kidney disease stage 3-5 have an increased risk of hypothyroidism. The risk factors include: gender, age, HbA1C, eGFR and urine ACR.