KHẢO SÁT TÌNH HÌNH SỬ DỤNG THUỐC ĐIỀU TRỊ ĐÁI THÁO ĐƯỜNG TÍP 2 VÀ TƯƠNG TÁC THUỐC TẠI KHOA KHÁM BỆNH – BỆNH VIỆN ĐA KHOA THỊ XÃ BUÔN HỒ NĂM 2023

Abstract

Objective: The purpose of this study was to assess the prescription of type 2 diabetes in the outpatient deparment of Buon Ho general Hospital and record drug interaction on clinical practice. Method: A cross – sectional study was used to assess the prescriprion of type 2 diabetes in the outpatient department of Buon Ho general Hospital from 01/01/2023 to 01/12/2023. There included 400 prescriptions in a study. Results: Biguanid group (metformin) is prescribed the most with 45.43%. Two-drug regimens account for the majority, with the combination sulfonylurea and metformin being prescribed the most at 81.12%. Insulin is being prescribes at 28.50%, with 100% insulin analog, oral antidiabetes drugs is prescribed at 71.50%.The ARB and CCB group was prescribed the most in hypertension with a rate of 58.94% and 22.08%. The 1-drug regimen is the most used with a rate of 91.64%. Statins are a group of drugs used 100% to treat dyslipidemia, atorvastatin is prescribed the most at 88.21%.The prevalence of potential drug – drug interactions was 21.5% with 20 drug - drug interaction pairs. Factors associated with potential drug- drug interactions were comorbidities (diabetes and hypertension (OR=36.838, P = 0,001); diabetes and hypertension and dyslipidemia (OR = 36.838, P = 0.001)), and number of active ingredients per prescriptions (OR= 12.669, P = 0.016).