ĐÁNH GIÁ KẾT QUẢ ĐIỀU TRỊ VIÊM MŨI DỊ ỨNG BẰNG LIỆU PHÁP MIỄN DỊCH DƯỚI LƯỠI MẠT BỤI NHÀ

Abstract

Objectives: Evaluate the results of treating allergic rhinitis with sublingual house dust mite immunotherapy. Methods: opinion overview. In this study, we used data on Pubmed and Google Scholar to search, screen related articles, analyze and evaluate the treatment results of sublingual immunotherapy for patients with allergic rhinitis are sensitive to house dust mites. Results: 18 eligible scientific studies were included in the review, over the last 10 years, of which 11 were randomized controlled clinical trials, 5 were prospective, and 2 were retrospective. describe each case with a total of 9319 patients. Sublingual immunotherapy was used in studies in different, standardized units: 10 studies used tablet form, 8 studies used drop form, treatment evaluation period from 12 to 48 months. 13 studies showed improvement in symptom score (SS) with p<0.05, 5 studies improved medication score (MS) P<0,05 6 studies found an improvement quality of life score (RQLQ) with p<0.05, 4 studies improved immune improvement, 15 studies evaluated the safety of SLIT. Conclusions: House dust mite sublingual immunotherapy is an effective treatment in reducing allergic rhinitis symptoms and patient's need for medication; improve quality of life and immune index;  it is a safe treatment method for both adults and children with allergic rhinitis.