NGHIÊN CỨU CHỈ SỐ HUYẾT SẮC TỐ HỒNG CẦU LƯỚI Ở TRẺ EM THIẾU MÁU THIẾU SẮT VÀ THALASSEMIA

Abstract

Background: Anemia is a common health problem in children. The most common cause of anemia is not getting enough iron. In countries with a high incidence of thalassemia disease, the common causes of anemia are not only iron deficiency but also thalassemia.  Reticulocyte hemoglobin content (CHr) and reticulocyte parameters are considered as the first signs in diagnosing the causes of microcytic anemia such as iron deficiency anemia or thalassemia. Objectives: Describe some hematological characteristics and compare reticulocyte hemoglobin content and reticulocyte parameters in children with iron deficiency anemia and thalassemia. Materials and methods: This cross-sectional descriptive study was conducted in 104 children diagnosed with iron deficiency anemia and thalassemia at Can Tho Children’s Hospital and Phuong Chau International Hospital. Results: Total of 104 children were enrolled with a median age of 3.0 years. Males accounted for 65.4% and females accounted for 34.6%. CHr in the iron deficiency anemia group was 23.4±3.7 pg and 25.0±2.4 pg in the thalassemia group, p<0.05. %Micro of the iron deficiency anemia group 44,9 (25,9-67) higher than thalassemia group 35 (16,2-52,4), with p<0,05. %Hypo in the iron deficiency anemia group and the thalassemia group were 50,5 (19,6-78,8) and 10,5 (4,1-18,9), p<0,001. MH in the iron deficiency anemia group were 0,91 (0,79-1,72) and 3,19 (1,73-5,51) in the thalassemia group, with p<0,001. Conclusions: This study shows the difference in mean values of CHr, %Micro, %Hypo, and MH between the iron deficiency anemia group and the thalassemia group