DEPRESSION IN PATIENTS WITH ACUTE LEUKEMIA
Main Article Content
Abstract
Background: Depression is common and often causes serious consequences on both the physical and mental health of patients with acute leukemia. The quality of life of patients and the economic burden associated with acute leukemia become more severe. Assessing the current state of depression will contribute to building a clinical picture of depression, thereby having strategies for prevention and treatment, improving the quality of life of these patients. Objectives: To evaluate the rate and some factors related to depressive disorders in patients with acute leukemia. Subjects and methods: Cross-sectional descriptive study on 82 acute leukemia patients at the Center for Hematology and Blood Transfusion - Bach Mai Hospital from August 2021 to August 2022, using the Beck depression assessment scale to determine depression. Results: The rate of depression was 50%, of which mild, moderate and severe levels were 23.2% 17.1% and 9.7%, respectively. There was a statistically significant association between the presence of other comorbidities, chemotherapy treatment methods and PS score ≥ 2 with depression. Conclusion: Depression screening measures are needed for early and appropriate intervention for acute leukemia patients at high risk of agitation.
Article Details
Keywords
depression, acute leukemia, related factors.
References
2. Malhi GS, Mann JJ. Depression. The Lancet. 2018; 392(10161): 2299-2312. doi:10.1016/ S0140-6736(18)31948-2
3. Salmon RM. The American Psychiatric Publishing Textbook of Psychosomatic Medicine. J Clin Psychiatry. 2007; 68(12):1990. doi:10.4088/ JCP.v68n1223a
4. Zhou F, Zhang W, Wei Y, et al. The changes of oxidative stress and human 8-hydroxyguanine glycosylase1 gene expression in depressive patients with acute leukemia. Leukemia Research. 2007; 31(3): 387-393. doi:10.1016/j.leukres. 2006.07.014
5. Dogu MH, Eren R, Yilmaz E, et al. Are We Aware of Anxiety and Depression in Patients with Newly Diagnosed Acute Leukemia? J Gen Pract. 2017;05(05). doi:10.4172/2329-9126.1000335
6. Suh KJ, Shin DY, Kim I, et al. Comparison of quality of life and health behaviors in survivors of acute leukemia and the general population. Ann Hematol. 2019;98(10): 2357-2366. doi:10.1007/ s00277-019-03760-5
7. Lennmyr EB, Karlsson K, Abrahamsson M, et al. Introducing patient-reported outcome in the acute leukemia quality registries in Sweden. European Journal of Haematology. 2020;104(6): 571-580. doi:10.1111/ejh.13399
8. Gheihman G, Zimmermann C, Deckert A, et al. Depression and hopelessness in patients with acute leukemia: the psychological impact of an acute and life-threatening disorder: Depression and hopelessness in patients with acute leukemia. Psycho-Oncology. 2016;25(8): 979-989. doi:10.1002/ pon.3940
9. Sørensen J, Klee M, Palshof T, Hansen H. Performance status assessment in cancer patients. An inter-observer variability study. Br J Cancer. 1993;67(4): 773-775. doi:10.1038/ bjc.1993.140