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CHARACTERISTICS OF NLR, PLR INDEX IN PATIENTS WITH HEPATOCELLULAR CANCINOMA
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Abstract
Objective: To investigate the characteristics of NLR, PLR in peripheral blood in patients with hepatocellular carcinoma. Subjects and methods: Cross-sectional descriptive study, with study group and control group. Study group: 60 newly diagnosed liver cancer patients who have not received treatment, came for examination and treatment in Military Hospital 103. Control group: 60 healthy people went for regular health check-ups. Results: The median of NLR in the study group were 2,60, higher than the control group, p < 0.05 and the median of PLR in the study group were 104,87, lower than the control group, p > 0.05. The NLR cutoff distinguishing the study group from the control group was 2.59, AUC area (95% CI) was 0.706 (0.61-0.79), p<0.05, with a specificity of 0.82. The AUC of PLR was 0,575; p > 0,05, which means no value in distinguishing the study group from control group. The difference in NLR according to The Barcelona Clinic Liver Cancer (BCLC) stage was statistically significant, p < 0.05. The difference in PLR according to BCLC stage was not statistically significant, p > 0.05. Conclusion: NLR indexes in the study group were higher than the control group, PLR indexes in the study group were lower than the control group. The NLR value was significant in distinguishing the study group and the control group with a cutoff point of 2.59. PLR did not distinguish the study group from the control group. NLR was associated with BCLC stage. PLR showed no association with BCLC stage
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Keywords
NLR, PLR index, hepatocellular cancinoma
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