HIỆU QUẢ PHƯƠNG PHÁP TRAO ĐỔI OXY QUA MÀNG NGOÀI CƠ THỂ TĨNH MẠCH – TĨNH MẠCH (VV ECMO) TRONG ĐIỀU TRỊ ARDS Ở PHỤ NỮ MANG THAI MẮC COVID-19 NGUY KỊCH

Abstract

Pregnant women with critical COVID-19 not responded to standard treatment will have high mortality, unless VV ECMO is implemented. In Vietnam, there hasn’t been study about effectiveness of VV ECMO on pregnant women with critical COVID-19. Objectives: To evaluate the effectiveness of VV ECMO on pregnant women with ARDS due to critical COVID-19. Methods: A retrospective study was carried out to evaluate effectiveness of VV ECMO on all pregnant women with ARDS due to critical COVID-19 who were not responded to standard treatment. Results: Total 17 pregnant women with ARDS due to critical COVID-19 treated VV ECMO (due to not responded to standard treatment) were included in the study with major of pregnant women had age of 30 years or more (range 18 – 40 years) and most fetuses had age of 28 weeks or more (range 22 – 38 weeks). Median time on COVID-19 and invasive mechanical ventilation before ECMO were 9.8 days (range 2 – 22 days) and 0.9 day (range 0.08 – 10 days), respectively. SOFA score and Murray score of pregnant women ranged from 4 to 11 points and from 3.0 to 3.8 points, respectively. Median time on VV ECMO of 20.2 days (1 – 57 days). Mortality rate was 17.6% for pregnant women and 11.8% for fetuses. Common complication on ECMO period were bleeding (12/17). Conclusion: VV ECMO was a high effective treatment for pregnant women with ARDS due to critical COVID-19 who were not responded to standard treatment.