ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG VÀ KẾT QUẢ ĐIỀU TRỊ UNG THƯ TINH HOÀN KHÔNG TINH BÀO TẠI BỆNH VIỆN K TỪ 2018 ĐẾN 2023

Abstract

Objectives: Describe the clinical and paraclinical characteristics and evaluate the survival time of patients with non-seminomatous testicular cancer at K Hospital. Methods: A retrospective descriptive study with longitudinal follow-up was conducted on 51 patients with non-seminomatous testicular cancer treated at K Hospital from January 2018 to December 2023. Progression-free survival (PFS) and overall survival (OS) were calculated using the Kaplan-Meier method. Results: The average age of the patients was 29 years, with the highest incidence observed in the 20-39 years age group, accounting for 64,7% of the cases. The rate of chemotherapy administration and/or radiation therapy following orchiectomy was 94%. The median PFS follow-up time was 41,1 months (95% CI: 31,0-51,1), with a 5-year PFS rate of 45,9%. The median OS follow-up time was 43,1 months (95% CI: 32,5-53,7), with a 5-year OS rate of 66,4%. The 5-year OS rate was significantly higher in patients with a complete biochemical response compared to those with a partial biochemical response (76,9% vs. 16,7%; p=0,001). Conclusions: Non-seminomatous testicular cancer predominantly affects younger males, with a significant proportion diagnosed at advanced stages. Survival rates vary significantly with biochemical response to treatment.