NGHIÊN CỨU ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG VÀ MỘT SỐ YẾU TỐ LIÊN QUAN ĐẾN LOÃNG XƯƠNG Ở BỆNH NHÂN SUY THƯỢNG THẬN MẠN

Abstract

Introduction: Chronic adrenal insufficiency is a common endocrine disease, especially in patients who abuse glucocorticoids and is one of the causes of osteoporosis. There are many studies around the world determining the rate of osteoporosis in patients with chronic adrenal insufficiency, however, in Vietnam, studies on this issue are still limited. Objectives: Describe clinical and subclinical characteristics and some factors related to osteoporosis in patients with chronic adrenal insufficiency. Meterials and methods: Cross sectional study of 77 patients with chronic adrenal insufficiency coming for examination and treatment at Kien Giang Provincial General Hospital from April 2023 to March 2024. Results: There was a total of 77 chronic adrenal insufficiency patients, women accounted for the majority with 83.1% and the average age was 69.8 ± 10.3 years. The rate of osteoporosis in chronic adrenal insufficiency patients was 84.4%. The most common symptom was bone pain. The mean bone density and T-score at the left and right femoral neck were 0.68 ± 0.15 g/cm2 and 0.67 ± 0.14 g/cm2, -2.58 ± 1.08 and -2.58 ± 0.95. There was a relationship between osteoporosis and factors such as gender, living situation and habits such as drinking milk regularly and regularly supplementing calcium. Conclusion: The rate of osteoporosis in patients with chronic adrenal insufficiency is 84.4%. The most common symptom is bone pain. There is a relationship between osteoporosis and factors such as gender, living situation and habits such as drinking milk regularly and regularly supplementing calcium.