ĐÁNH GIÁ TÁC DỤNG GIẢM BÉO PHÌ CỦA CAO LÁ VÀ CAO HOA TRÀ HOA VÀNG (CAMELLIA FLAVA (PITARD) SEALY) TRÊN MÔ HÌNH BÉO PHÌ TRÊN CHUỘT NHẮT TRẮNG BẰNG CHẾ ĐỘ ĂN GIÀU BÉO

Abstract

Objectives: Evaluating the anti-obesity effect of Camellia flava leaf and flower extract on high-fat diet-induced obesity in Swiss albino mice. Methods: Concentrated extracts from the leaf and flower of Camellia flava (Pitard) Sealy, Theaceae, were provided by Truong Duong Trading Investment Joint Stock Company. The ability of leaf and flower extracts to alleviate obesity induced by a high-fat diet (HFD) was studied using Swiss albino mice. After 2 months of being fed a higher fat content diet (40%), mice with the body weight 40% higher than their control counterparts receiving a standard diet of less than 5% lipid were divided into 5 groups, including control, HFD group, orlistat group, and 2 treatment groups receiving Camellia flava leaf extract of 1 g/kg and flower extract of 0,1 g/kg. Results: Groups of mice treated with both extracts exhibited a reduction of obesity along with improvements of blood lipid and liver histology. Conclusion: The leaf and flower extract have an anti-obesity effect on high-fat diet-induced obesity in Swiss albino mice.