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Date Published: 29/10/2024
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DOI: https://doi.org/10.51298/vmj.v543i3.11559
Issue
Vol. 543 No. 3 (2024)
Section
Các bài báo
How to Cite
Đoàn, D. Đạt, & Nguyễn, Q. T. (2024). OVERVIEW OF RESULTS OF RADIATION THERAPY FOR EARLY STAGE LARYNGEAL CANCER. Vietnam Medical Journal, 543(3). https://doi.org/10.51298/vmj.v543i3.11559

OVERVIEW OF RESULTS OF RADIATION THERAPY FOR EARLY STAGE LARYNGEAL CANCER

Duy Đạt Đoàn, Quang Trung Nguyễn

Main Article Content

Abstract

Objective: Describe the outcomes of radiotherapy for early stage laryngeal cancer. Study design: Scoping Review. Methods: We searched the database on the website Pubmed, the electronic library of Hanoi Medical University and manually searched on the results of radiotherapy for early stage laryngeal cancer. Results: We selected 12 studies published between 2006 and 2019 with 2298 patients treated with radiotherapy. The results of treatment with radiotherapy have a local control rate of stage T1 from 84% to 97.8%, a local control rate of stage T2 from 71.0% to 86.0%. Laryngeal preservation rate from 79.1% to 98.2%, overall survival rate in stage T1 from 87.0% to 98.0%, overall survival rate in stage T2 from 71.0% to 91 0%, disease-specific survival from 90.8% to 95.9%, disease-free survival from 67.2 to 89.7%, and voice disability score less than 10. Conclusion: Treatment of early stage laryngeal cancer with radiotherapy gives high local control rates, overall survival rates, disease-specific survival, disease-free survival, and larynx preservation. The local control rate and overall survival rate in stage T1 are better than those in stage T2, and voice quality is slightly damaged after radiotherapy.

Article Details

Keywords

Radiation therapy for early stage laryngeal cancer outcomes

References

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