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Date Published: 29/10/2024
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DOI: https://doi.org/10.51298/vmj.v543i3.11585
Issue
Vol. 543 No. 3 (2024)
Section
Các bài báo
How to Cite
Tôn, N. T. M., & Nguyễn, M. Đức. (2024). DIAGNOSTIC VALUE OF PITUTITARY GLAND VOLUME IN GIRLS WITH IDIOPATHIC CENTRAL PRECOCIOUS PUBERTY. Vietnam Medical Journal, 543(3). https://doi.org/10.51298/vmj.v543i3.11585

DIAGNOSTIC VALUE OF PITUTITARY GLAND VOLUME IN GIRLS WITH IDIOPATHIC CENTRAL PRECOCIOUS PUBERTY

Nữ Trà My Tôn, Minh Đức Nguyễn

Main Article Content

Abstract

Objective: This study aimed to evaluate the difference in pituitary size between girls with central precocious puberty (CPP) and normal girls by using cranial magnetic resonance imaging (MRI). Methods: Descriptive study was conducted on 78 girls, including 52 girls with central precocious puberty and 26 girls with normal development. Three-dimensional pituitary size and pituitary volume were measured. Results: Girls with central precocious puberty had significantly larger pituitary size than normal girls, especially in width (10.83mm vs. 9.23mm, p < 0.001) and pituitary volume (269.24 mm³ vs. 207.77 mm³, p < 0.001). Central precocious puberty had a statistically significant higher rate of convex pituitary shape, p = 0.004. The cut-off point of 260.44 mm³ was able to differentiate children with idiopathic central precocious puberty from normal puberty with an area under the curve of 0.71. Conclusion: The difference in pituitary size and volume between the two groups suggests an important role of the pituitary gland in the mechanism of central precocious puberty in girls.

Article Details

Keywords

Precocious puberty, idiopathic central precocious puberty, pituitary gland volume, convex pituitary shape.

References

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