VALUE OF CONTRAST ENHANCED SPECTRAL MAMMOGRAPHY IN DIAGNOSIS OF BREAST CANCER

Trần Thị Bích Hạnh1,, Nguyễn Minh Hải2, Vũ Thu Thủy1, Trần Thị Phương Thảo1, Lê Thị Thanh Xuân1
1 108 Military Central Hospital
2 Military Hospital 103, Vietnam Military Medical University

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Abstract

Objectives: To evaluate the diagnostic values of contrast enhanced spectral mammography (CESM) in patient withbreast cancer compared with histopathological results. Methods: Retrospective, cross-sectional study. Results: Studying on 50 patients with breast tumor lesions undergoing CESM, the average age was 49.86 ± 12.06. Multi-lobular mass on CESM had a sensitivity of 71.4%, specificity of 68.2%, a positive predictive value of 74.1% and a negative predictive value of 65.2%, with an accuracy of 60%. The indistinct margin mass on CESM had a sensitivity of 53.6%, a specificity of 77.3%, a positive predictive value of 75% and a negative predictive value of 56.7%, with an accuracy of 64%. Invasive tumor on CESM X-ray had a sensitivity of 42.9%, a specificity of 95.5%, a positive predictive value of 92.3% and a negative predictive value of 56.8%, with an accuracy of 66%. The image of enhancement on CESM had a sensitivity of 89.3%, a specificity of 90.9%, a positive predictive value of 92.6% and a negative predictive value of 87%, with an accuracy of 90%. The BIRADS classification ≥ 4 on CESM has a sensitivity of 96.4%, a specificity of 22.7%, a positive predictive value of 61.4% and a negative predictive value of 83.3%, with an accuracy of 64%. Conclusion: Image of CESM effectively evaluates hypedense lesions, clearly showing the mass nature, less omission of lesions, thus valuable in diagnosing breast cancer with subjects with dense mammary glands.

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References

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