ĐẶC ĐIỂM LÂM SÀNG VÀ KẾT QUẢ ĐIỀU TRỊ TẠI CHỖ VẢY NẾN MẢNG BẰNG CALCIPOTRIOL KẾT HỢP VỚI BETAMETHASONE

Abstract

Introduction: Psoriasis is a common skin disease that can affect people of all ages. It affects about 2% of the world's population. Plaque psoriasis is the most common type of psoriasis. One of the most common treatments for plaque psoriasis is the use of a topical combination of calcipotriol and betamethasone. However, there is relatively little research on the effectiveness of this topical treatment in Vietnam. Objective: Describe of clinical features in patients with plaque psoriasis and evaluation of the results of topical treatment of plaque psoriasis with topical calcipotriol combined with betamethasone. Subject and research method: A cross-sectional study was conducted Can Tho Hospital of Dermato-Venereology, including 80 patients diagnosed with plaque psoriasis, who were treated with calcipotriol combined with betamethasone topical ointment. The clinical features and treatment outcomes were recorded at 1, 2, 3, and 4 weeks of treatment. The study was conducted in 2023. Result: The mean age of onset was 47.2 ± 14.1 years. The most common site of current lesions was the trunk (87.5%). PASI before treatment: The mean PASI was 11 ± 2,71. The results showed that the PASI reduction was statistically significant with p<0.001 from week 2. The mean PASI after treatment was 5.22 ± 1.5. No cases of overdose were reported in the study. Conclusion: Calcipotriol/betamethasone topical ointment is an effective treatment for plaque psoriasis with many advantages, such as rapid PASI reduction and few adverse events… A unified procedure is needed when using the drug to minimize side effects in patients.