MỐI LIÊN QUAN GIỮA CHỈ SỐ SINH XƠ VỮA HUYẾT TƯƠNG (AIP) VÀ BÉO PHÌ

Abstract

Objective: To investigate the relationship between AIP, blood lipids and obesity. Subject and method: Cross-sectional descriptive study, conducted on 1307 people who came for regular health check-ups at Central Military Hospital 108 from January 1, 2023 to December 31, 2023. Blood lipid components were quantified by photometric method and AIP was calculated as log10 (TG/HDL-C). Results: The AIP index in the obese group was higher than the non-obese group, the difference was statistically significant (p=0.000). There was a strong positive correlation between AIP and BMI (r=0.528p=0.000). The fourth and third AIP quartiles had a higher risk of obesity than the first AIP quartile with OR of 4.86 and 2.36, respectively (p<0.01) after adjusting for the variables age, gender, systolic blood pressure, diastolic blood pressure, glucose, cholesterol, LDL-C. Area under the ROC curve of AIP in predicting obesity risk was 0.765 (0.736-0.794), cutoff point of 0.1247, sensitivity of 74% and specificity of 70%. Conclusion: The AIP index was a biomarker with moderate prognostic value in predicting the risk of obesity with an area under the ROC curve of 0.765 (0.736-0.794), sensitivity of 74% and specificity of 70%. AIP was strongly positively correlated with BMI (r=0.528, p<0.01).