ĐÁNH GIÁ TÁC DỤNG PHỤ CỦA FLUORESCEIN TRONG CHỤP MẠCH HUỲNH QUANG VÕNG MẠC

Abstract

Background: Since its introduction in 1961 by Novotny and Alvis, intravenous fluorescein angiography has been widely used to identify retinal and choroidal pathology. Fluorescein fundus angiography (FFA) is a valuable test used to investigate ocular circulation.  Although intravenous fluorescein angiography is a relatively safe procedure, a wide variety of adverse reactions and complications are described in literature after fluorescein angiography, ranging from mild to severe and rarely even causing death. Purpose: To describe adverse reactions of fluorescein angiography. Methods: This was a single-center, descriptive study that was initiated with 250 patients who undergone FFA for evaluation of adverse events between August 2023 to June 2024. An informed consent was obtained. All patients were ≥ 7 years of age. Exclusion criteria were pregnancy, nursing, a history of allergy to fluorescein, kidney failure, liver failure. Results: The mean age was 49,54 ± 15,35 (range 7-77 yo). Male/ female= 141/109. 7 patients have a history of alergy. No adverse events were seen in 89.2% (223 patients), mild adverse reactions were seen on 23 patients (9.2%), moderate reactions were seen on 4 patients (1.6%), No severe adverse reaction was seen. The most common side effects were nausea (6.8%, 17 patients). Conclusion: Our study indicates that FFA is a safe procedure. The most common side effects are nausea.