KHẢO SÁT TÌNH HÌNH SỬ DỤNG THUỐC ĐIỀU TRỊ Ở BỆNH NHÂN NHIỄM COVID-19 MỨC ĐỘ TRUNG BÌNH ĐẾN NGUY KỊCH TẠI BỆNH VIỆN ĐA KHOA ĐỒNG NAI

Abstract

Objective: To investigate the use of drugs in patients with moderate to critical COVID-19 at Dong Nai General Hospital. Methods: A cross-sectional descriptive study was conducted on 195 inpatients with COVID-19 aged 18 years and older who were treated from November 15, 2022 to June 15, 2023 at Dong Nai General Hospital. Medical information from COVID-19 patients was collected through handwritten medical records and HIS-FP software. Results: The median age and BMI of COVID-19 patients were 71 (61 – 82) and 22.1 (19.5 – 24.2) kg/m², respectively. The proportions of men and women were similar (49.7% and 50.3%, respectively). The most common comorbidities were digestive diseases (85.6%) and hypertension (59.5%). Patients were classified into 3 severity levels, including moderate (55.9%), severe (29.7%) and critical (14.4%) groups based on the classification standards of Vietnam Ministry of Health. Pharmacological treatments consisted of antiviral drugs (82.6%), corticosteroids (76.4%), enoxaparin (73.8%) and antibiotics (99.0%). The severity of the disease (OR = 2.213; 95% CI: 1.173 – 4.174; p=0.014) and the use of enoxaparin (OR = 3.907; 95% CI: 1.411 – 10.825; p = 0.009) were associated with duration hospital stay for more than 8 days. Conclusion: Prolonged hospital stays have been associated with the prescription of anticoagulants for COVID-19 patients.