EVALUATE THE RISKS OF OSTEOPOROSIS AND ASSOCIATED FACTORS IN PATIENTS WITH AKYLOSING SPONDYLITIS
Main Article Content
Abstract
Objective: describe the OSTA index and associated factors in patients diagnosed with akylosing spondylitis. Methods: a cross-sectional study was conducted among patients satisfied the diagnostic criteria of ACR-1984 in terms of akylosing spondylitis and was treated at Trung tâm cơ xương khớp – Bach Mai Hospital between 8/2023 and 5/2024. Recruited patients were clinically examined, underwent necessary blood test and measured bone density by DEXA scan. Results: 35 patients were eligible for the study, 62.9% were male, the mean age was 51.6 ± 7.8 with the prevalence of patients ≥60 years old of 20%. The mean OSTA index was 0.3 ± 2.64, lowest in those with osteoporosis (2.13 ± 1.19) and highest in those without osteoporosis (3.42 ± 1.57) (p <0.001). Based on OSTA index, the prevalence of patients at low, moderate and high risk of osteroporosis were 45.7%, 51.4%, and 2.9%, respectively. OSTA index was associated with low height, low weight, low BMI and low bone density at both femur and spine. Conclusion: Based on OSTA index, the majority of patients with akylosing spondylitis had low to moderate risk of osteoporosis. Associated factors related to OSTA index were height, weight, BMI, and bone density
Article Details
Keywords
OSTA, bone density, akylosing spondylitis
References

2. Hinze AM, Louie GH. Osteoporosis Management in Ankylosing Spondylitis. Curr Treatm Opt Rheumatol. 2016;2(4): 271-282. doi:10.1007/ s40674-016-0055-6


3. Kim JW, Park S, Jung JY, et al. Prevalence and Factors of Osteoporosis and High Risk of Osteoporotic Fracture in Patients with Ankylosing Spondylitis: A Multicenter Comparative Study of Bone Mineral Density and the Fracture Risk Assessment Tool. Journal of Clinical Medicine. 2022;11(10):2830. doi:10.3390/jcm11102830


4. Blake GM, Fogelman I. The role of DXA bone density scans in the diagnosis and treatment of osteoporosis. Postgrad Med J. 2007;83(982):509-517. doi:10.1136/pgmj.2007.057505


5. Koh LK, Sedrine WB, Torralba TP, et al. A simple tool to identify asian women at increased risk of osteoporosis. Osteoporos Int. 2001;12(8):699-705. doi:10.1007/s001980170070


6. Phùng Đức Tâm. Khảo sát chỉ số Z-score của mật độ xương ở bệnh nam viêm cột sống dính khớp. Luận văn Thạc sĩ Trường Đại học Y Hà Nội.

7. Sordia LH, Vazquez J, Iglesias JL, et al. Low height and low weight correlates better with osteoporosis than low body mass index in postmenopausal women. International Congress Series. 2004;1271: 407-410. doi:10.1016/ j.ics.2004.05.041


8. Muslim D, Mohd, E, Sallehudin, A, Tengku Muzaffar T, Ezane A. Performance of Osteoporosis Self-assessment Tool for Asian (OSTA) for Primary Osteoporosis in Post-menopausal Malay Women. Malays Orthop J. 2012;6(1):35-39. doi:10.5704/MOJ.1203.011

