ĐẶC ĐIỂM VIÊM DẠ DÀY RUỘT TĂNG BẠCH CẦU ÁI TOAN TẠI BỆNH VIỆN NHI ĐỒNG 2

Abstract

Background: Eosinophilic gastroenteritis is a rare chronic inflammatory disease characterized by focal or difuse eosinophilic infiltration in the gastrointestinal tract. Aim: This study depicts epidemiologic, clinical and subclinical characteristics of  children with eosinophilic gastroenteritis at Children's Hospital 2 from 01/2018 to 08/2024. Method: Case-series study. Results: Out of a total of 25 eosinophilic gastroenteritis patients. The male-to-female ratio was 2,1:1. The over-6-year-old group accounted for 84%. The 10 (40%) patients had a history of allergies. The most common manifestations were abdominal pain (84%) , vomiting (72%) and diarrhea (52%). Peripheral eosinophilia was present in 80% of the patients. The average eosinophil rate was 22,6±19,8%. The disease was classified as mucosal, subserosal and muscular in 72%, 20%, 8% of cases. The main locations of eosinophil infiltration were the ileum (72%) and colon (56%). Mean eosinophil counts/HPF in stomach (36,2±14), duodenum (75,5±54,3), ileum (257,5±198,3) and colon (92,1±21,1). Conclusion: Eosinophilic gastroenteritis was seen mainly in male, over - 6 year – old. The most common manifestations were abdominal pain, vomiting and diarrhea. Peripheral eosinophilia was present in 80% of the patients. The main site of eosinophilic infiltration was the ileum.