CLINICAL, SUBCLINICAL CHARACTERISTICS OF PANCREATIC CANCER AT MILITARY HOSPITAL 175
Main Article Content
Abstract
Objectives: To describe the clinical, laboratory and imaging characteristics of the pancreatic cancer cases at the Institute of Oncology and Nuclear Medicine, Military Hospital 175. Patients and methods: Retrospective descriptive study on 66 patients was diagnosed pancreatic cancer at the Institute of Cancer and Nuclear Medicine - Military Hospital 175 from January 2020 to December 2023. Results: The study enrolled 66 patients (male/female = 2.3/1, mean age 62.1, mostly older than 60 years old (63.6%)). The main presenting symptoms was abdominal pain (75.8%), the average tumor size was 4.56 cm on the CT scan, the percentage of the head and tail pancreatic cancer cases was the same. The blood value of CA 19-9 greater than 35 U/ml was 82.8% of the presenting cases. 26 of the 66 cases had no histological proof, confirmed by CT scan imaging and elevated CA 19-9. Adenocarcinoma was the most common type of pancreatic cancer with 72.5% of the cases. 43 of the 66 patients had stage 4 pancreatic cancer (65.2%). Conclusion: Pancreatic cancer was the rapid - progressing cancer mostly seen in elderly 60 years old patients. The biopsy of the pancreatic tumor was difficult. The presenting cases were diagnosed at the late stage of the disease, which has poor prognosis.
Article Details
Keywords
pancreatic cancer, clinical characteristics, laboratory imaging
References

2. Nguyễn Minh Ngọc, Nhận xét đặc điểm lâm sàng và cận lâm sàng ung thư tụy tại bệnh viện K và bệnh viện Đại học Y Hà Nội. Luận văn tốt nghiệp bác sĩ đa khoa (2013).

3. Nguyễn Bá Đức, Trần Văn Thuấn, Nguyễn Tuyết Mai (2010), Ung thư tụy, Điều trị nội khoa bệnh ung thư. Nhà xuất bản Y học, 189-199.

4. Võ Đức Hiếu và cộng sự. Hiệu quả và tính an toàn của điều trị toàn thân bước 1 ung thư tụy tiến xa/ di căn, tái phát tại khoa nội tuyến vú, tiêu hóa, gan, niệu từ tháng 6/2021- đến tháng 6/2023- bệnh viện ung bướu thành phố Hồ Chí Minh, Hội thảo hàng năm phòng chống ung thư Tp Hồ Chí Minh lần thứ 26.

5. Genkinger J.M., Spiegelman D., Anderson K.E et al, Alcohol intake and pancreatic risk: a pooled analysis of fourteen cohort studies, Epidermiol Biomark Prev Publ Am Assoc Cancer Res Cosponsored Am Soc Prev Oncol 18, 2009 (3), 765-776

6. Global Cancer Stasics 2020, GLOBOCAN Estimates of Incidence and Mortality Pancreatic cancer in Viet Nam, CA Cancer J Clin. 2021.

7. Bray F, Laversanne M, Sung H, et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: a cancer journal for clinicians. 2024;74(3):229-263.

8. Heinemann V, Labianca R, Hinke A, Louvet C. Increased survival using platinum analog combined with gemcitabine as compared to single-agent gemcitabine in advanced pancreatic cancer: pooled analysis of two randomized trials, the GERCOR/GISCAD intergroup study and a German multicenter study. Annals of oncology. 2007;18(10):1652-1659.
