ĐẶC ĐIỂM GIẢM ĐỘ BÃO HÒA OXY TRONG MÁU KHI NGỦ Ở BỆNH NHÂN BỆNH PHỔI TẮC NGHẼN MẠN TÍNH

Abstract

Background: Chronic obstructive pulmonary disease (COPD) is a chronic respiratory disease with many complex mechanisms that cause disorders of blood gas components in acute and chronic conditions. Nocturnal oxygen desaturation is a common condition in COPD patients, contributing to the progression of the disease and the risk of death. Objectives: 1) To determine the prevalence of oxygen desaturation, intermittent hypoxia and continuous hypoxia at night in patients with COPD; 2) To describe characteristics of patient and nocturnal oxygen desaturation in patients with COPD. Materials and methods: Cross-sectional descriptive study, randomly selected 65 COPD patients being managed from April 2023 to October 2024 at the Respiratory Unit, Can Tho University of Medicine and Pharmacy Hospital. Results: The mean age of the patients was 73,6 ± 9,24 and the male proportion was 98,5%, a mean BMI of 21,09 ± 3,59 kg/m², a mean FEV₁ of 51,31 ± 20,0%, the rate of groups A:B:E was 16.9%: 26.9%: 46.2% and the prevalence of comorbidities with heart failure: hypertension: type 2 diabetes: OSA was 3.1%: 64.6%: 29.2%: 50.8% respectively. The characteristic of nocturnal oxygen desaturation was recorded by the average ODI indicators of 8.17 ± 10.12 events/hour, Mean SpO2 was 91.79 ± 2.51%, minimal SpO2 was 80.73 ± 6.74%, a mean T90 of 129.74 ± 138.6 minutes, a mean T85 of 17.8 ± 38.45 minutes. The prevalence of nocturnal oxygen desaturation, intermittent hypoxia and continuous hypoxia at night were 80%, 29.2% and 50.8% respectively in COPD patients. Conclusions: Nocturnal oxygen desaturation is a common condition in patients with COPD. The frequency of continuous hypoxia at night is high and has characteristics, including significantly lower mean and minimal SpO2 values and longer sleep duration in patients with SpO2 below 90% and 85% compared with patients with intermittent hypoxia.