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Date Published: 18/10/2021
Abstract Views: 561
Views PDF: 202
DOI: https://doi.org/10.51298/vmj.v506i1.1178
Issue
Vol. 506 No. 1 (2021)
Section
Các bài báo
How to Cite
Thị Hà, N. ., & Lê Huy, T. . (2021). RESULTS OF NEOADJUVANT CONCURRENT CHEMORADIOTHERAPY IN STAGE II-III MIDDLE-LOWER THIRD ESOPHAGEAL CANCER AT 108 CENTRAL MILITARY HOSPITAL. Vietnam Medical Journal, 506(1). https://doi.org/10.51298/vmj.v506i1.1178

RESULTS OF NEOADJUVANT CONCURRENT CHEMORADIOTHERAPY IN STAGE II-III MIDDLE-LOWER THIRD ESOPHAGEAL CANCER AT 108 CENTRAL MILITARY HOSPITAL

Nguyễn Thị Hà1, Trịnh Lê Huy2,
1 108 Military Central Hospital
2 Department of Oncology, Hanoi Medical University

Main Article Content

Abstract

Objectives:To assess the treatment results of neoadjuvant chemoradiation in the middle and lower thirds, stage II, III esophageal cancer patients at the 108 Military Central Hospital. Subject and method:A retrospective and prospective descriptive study with 44 stage II-III esophageal cancer patientsunderwent preoperative, concurrent chemotherapy with paclitaxel/carboplatin and radiation with a dose of41.4Gy/23fx followed by surgery. Results: The means age was 55 years old, the percentage of malewas 97,7%. The dysphagia rate was 81,8, weight loss was found in 27/44 (61,2%), the mean length of tumor is 6 ±0.25 cm. The subclinical complete responses were 38.6%. The pathology complete response was 43.2% (pT0N0) and R0 resection was achieved for 41 patients (93.2%). Side effects fatigue, esophageal mucositis, and leukopenia, most of which were in grade 1-2.Conclusions:Preoperative chemoradiation in an effective treatment for stgage II-III esophageal cancer patients with acceptable side effects, complications, and surgical complications.

Article Details

Keywords

Esophageal cancer, preoperative chemoradiotherapy

References

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