ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG CỦA BỆNH NHÂN U TUYẾN THƯỢNG THẬN ĐƯỢC PHẪU THUẬT TẠI BỆNH VIỆN TRUNG ƯƠNG QUÂN ĐỘI 108

Abstract

Objective: Description of clinical and paraclinical characteristics of patients with adrenal tumors who underwent surgery at 108 Central Military Hospital. Subjects and methods: Cross-sectional descriptive study on 70 patients with adrenal tumors who underwent surgery at 108 Central Military Hospital from January 2023 to June 2024. Results: In the aldosterone-secreting group, the mean age was 50.76 years; 42.9% were female; 100% of patients had hypertension on admission; the proportion of patients with hypokalemia on admission was 90.5%; the proportion of patients with ARR > 3.8 was 95.2%; 81% of patients had tumors on the left side, the average tumor size measured on CT was 1.70 ± 0.59 cm. In the cortisol-secreting group, the mean age of patients was 27.50 years; all patients in this group were female, 100% of patients had a history of hypertension and ACTH test results < 5 pg/ml; 75% of patients had tumors on the left side, the average tumor size on CT was 6.95 ± 4.95 cm. In the pheochromocytoma group, the mean age of patients was 56.25 years; all patients in this group were male; 50% of patients had hypertension on admission; 75% of patients had tumors on the left side, the mean tumor size on CT was 5.68 ± 2.45 cm. In the incidentally discovered group, the mean age was 51.95 years; the proportion of female patients was 43.9%; 51.2% of patients had tumors on the left side, the mean tumor size on CT was 4.36 ± 2.27 cm; the proportion of aldosterone-secreting tumors was 12.2%, cortisol-secreting tumors was 22%, pheochromocytoma was 22%, and nonsecreting tumors was 43.9%. Conclusion: Adrenal tumors can present clinically with different symptoms and syndromes depending on the nature of the tumor. Computed tomography plays a key role in detecting adrenal tumors, and biochemistry is needed to determine the nature of the lesion.