Article Sidebar

pdf
Date Published: 26/11/2024
Abstract Views: 96
Views pdf: 74
DOI: https://doi.org/10.51298/vmj.v544i2.11820
Issue
Vol. 544 No. 2 (2024)
Section
Các bài báo
How to Cite
Trần, T. V., Phan, T. A. T., Dương, H. K. L., Vũ, T. H. Y., & Nguyễn, C. T. (2024). STUDY ON SMALL DENSE LDL CONCENTRATION USING COLORIMETRIC ENZYME METHOD IN PATIENTS WITH ACUTE CORONARY SYNDROME AT CHO RAY HOSPITAL. Vietnam Medical Journal, 544(2). https://doi.org/10.51298/vmj.v544i2.11820

STUDY ON SMALL DENSE LDL CONCENTRATION USING COLORIMETRIC ENZYME METHOD IN PATIENTS WITH ACUTE CORONARY SYNDROME AT CHO RAY HOSPITAL

Thành Vinh Trần, Thị Anh Thư Phan, Hà Khánh Linh Dương, Thị Hải Yến Vũ, Chí Thanh Nguyễn

Main Article Content

Abstract

Objective: To determine the concentration of small dense LDL-C (sdLDL-C) and the association between sdLDL-C concentration with lipid components and some clinical and subclinical factors in patients with acute coronary syndrome at Cho Ray Hospital. Methods: A cross-sectional study surveyed 114 patients with acute coronary syndrome (ACS) at the Department of Cardiology and Interventional Cardiology at Cho Ray Hospital, from March 2023 to November 2023. sdLDL-C was quantified by colorimetric enzyme method. Results: The sdLDL-C concentration was 37.5 (21.4 - 60.9) mg/dL. sdLDL-C was strongly correlated with total cholesterol and LDL-C (r>0.5; p<0.001); moderate correlation with triglycerides and age. Conclusion: sdLDL-C levels may have value in the assessment of dyslipidemia

Article Details

Keywords

: Acute coronary syndrome, LDL-C, sdLDL-C

References

1. World Health Organization, Cardiovascular diseases (CVDs). Updated 11 June 2021. 2021.
2. Hoogeveen, R.C., et al., Small dense low-density lipoprotein-cholesterol concentrations predict risk for coronary heart disease: the Atherosclerosis Risk In Communities (ARIC) study. Arterioscler Thromb Vasc Biol, 2014. 34(5): p. 1069-77.
3. Ivanova, E.A., et al., Small Dense Low-Density Lipoprotein as Biomarker for Atherosclerotic Diseases. Oxid Med Cell Longev, 2017. 2017: p. 1273042.
4. Fukushima, Y., et al., Small dense LDL cholesterol is a robust therapeutic marker of statin treatment in patients with acute coronary syndrome and metabolic syndrome. Clin Chim Acta, 2011. 412(15-16): p. 1423-7.
5. Karthikeyan, T., et al., Risk factors and inflammatory markers in acute coronary syndrome-ST elevation myocardial infarction (STEMI). Horm Mol Biol Clin Investig, 2023. 44(2): p. 115-120.
6. Singh, A., et al., Small Dense Low-Density Lipoprotein for Risk Prediction of Acute Coronary Syndrome. Cardiol Res, 2021. 12(4): p. 251-257.
7. Enkhmaa, B., E. Anuurad, and L. Berglund, Lipoprotein (a): impact by ethnicity and environmental and medical conditions. J Lipid Res, 2016. 57(7): p. 1111-25.
8. Imamura, T., et al., Estimation of Small Dense LDL-Cholesterol Levels in Patients with Acute Coronary Syndrome. Int Heart J, 2023. 64(4): p. 596-601.