KẾT QUẢ ĐIỀU TRỊ NỘI KHOA KẾT HỢP LIỆU PHÁP TIÊM COLLAGEN CẠNH CỘT SỐNG Ở BỆNH NHÂN THOÁT VỊ ĐĨA ĐỆM CỘT SỐNG THẮT LƯNG TẠI BỆNH VIỆN TRUNG ƯƠNG THÁI NGUYÊN

Abstract

Objective: To evaluate the outcomes of medical treatment combined with paraspinal collagen injection in patients with lumbar disc herniation at Thai Nguyen National Hospital. Subjects and Methods: A longitudinal intervention study with a 12-week follow-up on 61 patients with lumbar disc herniation, divided into two groups: The study group consisted of 30 patients who received basic medical treatment combined with lumbar paraspinal collagen MD injections. The control group included 31 patients who received basic medical treatment combined with epidural hydrocortisone injections. Results: After 12 weeks, the average VAS score in the study group decreased from 6.27 ± 0.83 to 0.63 ± 0.56, which was lower than that of the control group (p < 0.05). In the study group, 100% of patients showed improvement in lumbar spine flexibility and daily functioning at a good or very good level, higher than the control group (p < 0.05). Most patients in both groups had overall treatment outcomes at good or higher levels, with the study group showing a significantly higher rate of very good improvement (93.3%) compared to the control group (22.6%) (p < 0.05). No adverse effects were observed in the study group, whereas 19.4% of patients in the control group experienced increased pain after injection. Conclusion: Paraspinal collagen injection therapy is more effective and safer than epidural hydrocortisone injection in treating lumbar disc herniation.