Article Sidebar
Views pdf: 43
RISK FACTORS OF EARLY ONSET NEONATAL SEPSIS IN VINMEC TIMES CITY INTERNATIONAL HOSPITAL
Main Article Content
Abstract
Objectives: This study aimed to describe factors related to early onset neonatal sepsis in Vinmec Times City International Hospital. Subject and methods: A cross-sectional study was conducted at Vinmec Times City International Hospital, enrolling 124 newborns with early onset neonatal sepsis and 248 healthy newborns in the control group from 01/2023 to 12/2023. Results: The results showed that factors related to early onset sepsis including (1) maternal factors: intrapartum fever (OR 26,4 95% CI [11,5 – 60,4]), genital infection (OR 2,3; 95% CI [1,1 - 4,9]), (2) neonatal risk factors: premature birth (OR 3,1; 95% CI [1,8 – 5,3]), low birth weight (OR 4,4; 95% CI [1,7 - 11,3]), APGAR score at 1 minute < 7 (OR 5,7; 95% CI [3,4 - 11,7]), (3) birth related factors: premature rupture of membrane (OR 3,0; 95% CI [1,7 - 5,5]), abnormal amniotic fluid (OR 5,5; 95% CI [2,3 - 10,7]) and prolonged labor period (2,7 [1,1 - 6,7]). Conclusions: Accurately identifying risk factors in neonatal sepsis helps early diagnosis, thereby improving treatment effectiveness and preventing unnecessary antibiotic use.
Article Details
Keywords
Nhiễm khuẩn sơ sinh sớm, nhiễm khuẩn sơ sinh
References
2. NICE. Neonatal infection: determining the need for antibiotic treatment of babies within 72 hours of birth. Neonatal infection: antibiotics for prevention and treatment. 2021.
3. Shifera N, Dejenie F, Mesafint G, et al. Risk factors for neonatal sepsis among neonates in the neonatal intensive care unit at Hawassa University Comprehensive Specialized Hospital and Adare General Hospital in Hawassa City, Ethiopia. 2023;11.
4. Khalesi N, Khosravi N, Jalali A, et al. Evaluation of maternal urinary tract infection as a potential risk factor for neonatal urinary tract infection. Journal of family & reproductive health. 2014;8(2):59-62.
5. Rallis D, Lithoxopoulou M, Pervana S, et al. Clinical chorioamnionitis and histologic placental inflammation: association with early-neonatal sepsis. The Journal of Maternal-Fetal & Neonatal Medicine. 2022;35(25):8090-6.
6. Masanja PP, Kibusi SM, Mkhoi ML et al. Predictors of Early Onset Neonatal Sepsis among Neonates in Dodoma, Tanzania: A Case Control Study. Journal of tropical pediatrics. 2020; 66(3):257-66.
7. Murthy S, Godinho MA, Guddattu V, et al. Risk factors of neonatal sepsis in India: A systematic review and meta-analysis. PloS one. 2019;14(4):e0215683.
8. Moftian N, Samad Soltani T, Mirnia K, et al. Clinical Risk Factors for Early-Onset Sepsis in Neonates: An International Delphi Study. Iranian journal of medical sciences. 2023;48(1):57-69.